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ADAM17 — NOS2

Text-mined interactions from Literome

Hurtado et al., Neuropharmacology 2001 (Brain Ischemia) : Taken together, these data demonstrate that ( 1 ) TACE/ADAM17 activity accounts for the majority of TNF-alpha shedding after OGD in rat forebrain slices, ( 2 ) an increase in TACE expression contributes, at least in part, to the rise in TNF-alpha after OGD and ( 3 ) iNOS expression in OGD subjected brain slices results from TACE activity and subsequent increase in TNF-alpha levels
Madrigal et al., Biol Psychiatry 2002 : In order to study the role of TACE and TNF-alpha in iNOS induction, a group of animals were i.p. injected with the preferred TACE inhibitor BB1101 ( 2 and 10 mg/kg )
Yang et al., Int Immunol 2005 : Transfection of ADAM3/PCDNA3.1 ( + ) up-regulated the expression of AIF-1 and iNOS, whereas suppression of ADAM3 expression down-regulated AIF-1 and iNOS expression