Gene interactions and pathways from curated databases and text-mining

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CSE — IL6

Text-mined interactions from Literome

Kode et al., Respir Res 2006 : CSE , however, induced IL-8 and IL-6 release in primary cell lines in a dose dependent manner, which was associated with the nuclear translocation of NF-kappaB in SAEC
Liu et al., Biochem Biophys Res Commun 2007 : CSE also stimulates IL-6 release and mRNA expression
Mortaz et al., Respir Res 2009 : We observed that CSE augmented the production of IL-8 and suppressed the release of TNF-alpha, IL-6 and IFN-alpha
Milara et al., Eur J Pharm Sci 2010 : CSE ( 2.5-10 % ) induced upregulation of IL-6 , IL-8 and Ang-2, and decreased Ang-1 expression in parallel to apoptosis which were partially suppressed by sildenafil, 8-Br-cGMP, DPI and NAC
Mo et al., Toxicol In Vitro 2012 : Furthermore, UFPs- and/or CSE induced Egr-1 mRNA upregulation was attenuated significantly when cells were pre treated with p38 specific inhibitor, SB 203580, or MEK1/2 inhibitor, PD98059, and Egr-1 siRNA treatment abolished UFPs- and/or CSE induced overexpression of IL-6