Gene interactions and pathways from curated databases and text-mining

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PDGFD — VEGFA

Text-mined interactions from Literome

Wang et al., Cancer Res 2007 (Adenocarcinoma...) : Our data showed that down-regulation of PDGF-D leads to the inactivation of Notch-1 and NF-kappaB DNA binding activity and, in turn, down regulates the expression of its target genes, such as VEGF and MMP-9
Zhao et al., Cancer Biol Ther 2010 (Neoplasm Invasiveness...) : Further, downregulation of PDGF-D remarkably reduced VEGF expression and secretion and proangiogenic activities of SGC-7901 cells in vitro