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CAT — TNF
Text-mined interactions from Literome
Naitoh et al., Cell Signal 2001
(Insulin Resistance) :
Catalase completely
inhibited GHA induced
TNF-alpha release ; however, superoxide dismutase ( SOD ) had no effect
Chen et al., J Pharmacol Exp Ther 2003
:
In contrast, Ad.N17Rac1 inhibited
TNF-alpha induced NF-kappaB-driven HIV ( kappaB ) ( 4 )
-CAT and p288VCAM-Luc promoter activity, suggesting that N17Rac1 inhibits TNF-alpha induced VCAM-1, E-selectin, and ICAM-1 through suppressing NF-kappaB mediated transactivation
Campo et al., Life Sci 2004
(Carbon Tetrachloride Poisoning...) :
Carbon tetrachloride produced a marked increase in serum alanine aminotransferase and aspartate aminotransferase activities, primed lipid peroxidation, enhanced plasma
TNF-alpha levels,
induced a severe depletion of reduced glutathione and
catalase , and promoted neutrophil accumulation
Lecour et al., Cardiovasc Res 2005
(Myocardial Ischemia...) :
TNF alpha-perfusion increased
catalase activity in the ventricles ( 15.8+/-1.2 I.U./mg for controls vs. 19.9+/-1.1 I.U/mg for TNF alpha, p < 0.05 )
Xing et al., Chin Med J (Engl) 2005
(Hepatitis B, Chronic) :
The activity of the
CAT gene at these point mutations of HPRE could be
inhibited by IFN-alpha/gamma and
tumor necrosis factor (TNF)-alpha except for the point mutations at nt 1508 of HPRE which may escape the suppression role of IFN-alpha on HPRE
Basuroy et al., Am J Physiol Cell Physiol 2006
:
The
TNF-alpha response was
inhibited by superoxide dismutase and
catalase suggesting apoptosis is oxidative stress related
Jekabsone et al., Journal of neuroinflammation 2006
:
Production of
TNF-alpha and IL-1beta, measured after 24 hours of Abeta treatment, was also
prevented by apocynin,
catalase and EUKs, but the early release ( measured after 1 hour of Abeta treatment ) of TNF-alpha was insensitive to apocynin or catalase
Imrich et al., Toxicol Appl Pharmacol 2007
:
N-Acetyl-l-cysteine ( 20 mM ), dimethyl thiourea ( 20 mM ) and
catalase ( 5 microM ) significantly
inhibited TNF release by primed AMs incubated with CAPs
Hu et al., J Ethnopharmacol 2008
(Drug-Induced Liver Injury) :
Pretreatment with CGX significantly restored the reduction of
catalase activity and glutathione ( GSH ) content, but not superoxide dismutase ( SOD ) activity, and it
inhibited the CCl ( 4 ) -induced high expression of iNOS and
TNF-alpha in hepatic tissue
Siwale et al., Journal of drug targeting 2009
(Disease Models, Animal...) :
Microencapsulated ( MC )
catalase has been shown to
inhibit H ( 2 ) O ( 2 ) and
tumor necrosis factor (TNF) in vitro after endotoxin stimulation
Matsuda et al., J Biol Chem 2010
:
ClC-3 expression induced ICl ( swell ) in ClC-3 null cells in the absence of swelling or
TNF-alpha , and this effect was also
blocked by
catalase
Omary et al., AIDS 1991
:
In SW620 and HT29 cells transfected with the HIV-1 long terminal repeat ( LTR ) linked to the chloramphenicol acetyl transferase (CAT) reporter gene, an intact HIV-1 enhancer element was required for
stimulation of
CAT activity by
tumor necrosis factor alpha (TNF alpha) and phorbol ester
Latham et al., Cell Immunol 1990
:
In this model system, endotoxin lipopolysaccharide (LPS) and
tumor necrosis factor-alpha (TNF-alpha) are able to independently
stimulate expression of
LTR-CAT
Suzuki et al., Biochem Biophys Res Commun 1995
:
Transient overexpression of
catalase does not
inhibit TNF- or PMA induced NF-kappa B activation ... Overexpression of
catalase , however, did not
block TNF- or PMA induced NF-kappa B activation
Nanes et al., Endocrinology 1994
:
TNF alpha inhibited 1,25- ( OH ) 2D3 stimulated, but not basal,
CAT activity
Flad et al., Arch Immunol Ther Exp (Warsz) 1995
(Leprosy, Lepromatous...) :
Furthermore, M. kansasii with high intrinsic catalase
induce less
TNF-alpha than mycobacteria with low intrinsic
catalase