Gene interactions and pathways from curated databases and text-mining

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CXCL17 — IL6

Text-mined interactions from Literome

Kim et al., Int Immunopharmacol 2010 (Inflammation...) : In a cellular model of inflammation, DMC inhibited production of nitric oxide ( NO ) and prostaglandin E ( 2 ) ( PGE ( 2 ) ) and attenuated expression of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) , IL-1 beta, inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2)
Lai et al., Int J Gynecol Cancer 2011 (Genital Neoplasms, Female...) : Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2, CXCL2 , IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2, CCL20, CXCL1, CXCL2, IL-6 , and IL-8 increased
Lee et al., J Immunol 2012 : CCR1 mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive Ga ( 14/16 ) signaling and IL-6 release
Shieh et al., J Agric Food Chem 2013 : Moreover, DMC suppressed LPS induced IL-6 production, thereby blocking subsequent Stat3 activation