Gene interactions and pathways from curated databases and text-mining

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GRAP2 — IL24

Text-mined interactions from Literome

Ling et al., Crit Care Med 2002 : In contrast to its effects on the janus kinase/STAT pathways, interleukin-6 activation of MAP kinases ( extracellular signal regulated kinase-1, extracellular signal regulated kinase-2, and p38 ) was unaffected by endotoxin
Yan et al., J Biol Chem 2002 : This model probiotic also inhibits activation of the pro-apoptotic p38/mitogen activated protein kinase by tumor necrosis factor, interleukin-1alpha , or gamma-interferon
Yacoub et al., Mol Cancer Ther 2008 (Glioblastoma) : In GBM6 cells, GST-MDA-7 ( 30 nmol/L ) transiently activated p38 mitogen activated protein kinase, which was modestly protective against JNK1-3 induced toxicity, whereas GST-MDA-7 ( 300 nmol/L ) caused prolonged intense p38 mitogen activated protein kinase activation, which promoted cell death
Rasheed et al., Arthritis Res Ther 2010 (Osteoarthritis) : Pomegranate extract inhibits the interleukin-1ß induced activation of MKK-3, p38a-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes