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GRAP2 — IL24
Text-mined interactions from Literome
Ling et al., Crit Care Med 2002
:
In contrast to its effects on the janus kinase/STAT pathways,
interleukin-6 activation of MAP kinases ( extracellular signal regulated kinase-1, extracellular signal regulated kinase-2, and
p38 ) was unaffected by endotoxin
Yan et al., J Biol Chem 2002
:
This model probiotic also inhibits
activation of the pro-apoptotic
p38/mitogen activated protein kinase by tumor necrosis factor,
interleukin-1alpha , or gamma-interferon
Yacoub et al., Mol Cancer Ther 2008
(Glioblastoma) :
In GBM6 cells, GST-MDA-7 ( 30 nmol/L ) transiently activated p38 mitogen activated protein kinase, which was modestly protective against JNK1-3 induced toxicity, whereas
GST-MDA-7 ( 300 nmol/L )
caused prolonged intense
p38 mitogen activated protein kinase activation, which promoted cell death
Rasheed et al., Arthritis Res Ther 2010
(Osteoarthritis) :
Pomegranate extract inhibits the
interleukin-1ß induced activation of MKK-3,
p38a-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes