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EPAS1 — MYC

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: MYC → EPAS1 (increases, EPAS1 Activity)
  Evidence: Unlike HIF-1, HIF-2 promotes C-Myc-dependent activation of cyclin D2 and repression of p27 in RCC cells.74

Text-mined interactions from Literome

Gordan et al., Cancer Cell 2007 (Colonic Neoplasms) : As HIF-1alpha antagonizes c-Myc function, we hypothesized that HIF-2alpha might enhance c-Myc activity
Yoon et al., J Mol Med (Berl) 2010 (Polycythemia) : In contrast, HIF-2alpha promotes MYC activity and cell proliferation