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EGFR — RAF1

Text-mined interactions from Literome

Zhang et al., Lab Invest 2002 (Breast Neoplasms) : EGFR and ErbB2 differentially regulate Raf-1 translocation and activation
Cappuzzo et al., J Natl Cancer Inst 2004 (Carcinoma, Non-Small-Cell Lung...) : Phosphatidylinositol 3'-kinase (PI3K)/Akt and Ras/Raf/mitogen activated protein kinase ( MAPK ), the two main EGFR signaling pathways, mediate EGFR effects on proliferation and survival
Schnidar et al., Cancer Res 2009 (Cell Transformation, Neoplastic...) : Here, we provide evidence that integration of the HH/GLI and epidermal growth factor receptor (EGFR) pathway synergistically induces oncogenic transformation, which depends on EGFR mediated activation of the RAS/RAF/MEK/ERK but not of the PI3K/AKT pathway
Scartozzi et al., Journal of translational medicine 2012 (Colorectal Neoplasms...) : The EGFR pathway activation via the Ras-Raf-MAP-kinase and the protein-serine/threonine kinase AKT could determine resistance to anti-EGFR treatment