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MAPK8 — WNK1
Text-mined interactions from Literome
Rahman et al., Am J Physiol Lung Cell Mol Physiol 2004
:
Because p38
MAPK can
induce transcriptional activity of
RelA/p65 without altering the DNA binding function of NF-kappaB, we addressed the possibility that cAMP antagonizes thrombin induced NF-kappaB activity and ICAM-1 expression by preventing the activation of p38 MAPK
Syeda et al., J Biol Chem 2006
:
Activation of PAR-1 or PAR-2 promoted nuclear translocation and phosphorylation of
p65-NF-kappaB , and thrombin induced but not PAR-2 induced p65-NF-kappaB phosphorylation was
reduced by inhibition of MEK or
p38MAPK
Kim et al., Microbes Infect 2006
(Fibrosarcoma...) :
In addition, although phosphorylation of NF-kappaB
p65 in spleen was equally enhanced in the ATCC27139- and the ATCC27139-J1R treated groups, phosphorylation of both p38
MAPK and MAPKAPK-2 was significantly
induced only by ATCC27139
El-Bikai et al., Arthritis Res Ther 2010
(Osteoarthritis) :
It
inhibited a1ß1 integrin and Col II expression as well as ERK1/2 and
NF-?B-p65 phosphorylation, but, in contrast, markedly elicited PGE2 release, COX-2 expression and p38
MAPK phosphorylation