Gene interactions and pathways from curated databases and text-mining

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EMD — GJA1

Text-mined interactions from Literome

Stanbouly et al., J Pharmacol Exp Ther 2008 : Increased Cx43 expression observed with PE treatment ( 132.4 +/- 6.3 % compared to control ; P < 0.05 ) was further significantly augmented by the specific NHE-1 inhibitor EMD87580 [ N- [ 2-methyl-4,5-bis ( methylsulfonyl ) -benzoyl ] -guanidine hydrochloride ] ( 173.2 +/- 8.7 % increase compared to control ; P < 0.05 versus PE ), an effect that was mimicked by another NHE-1 inhibitor cariporide [ 4-isopropyl-3- ( methylsulfonyl ) benzoyl-guanidine methanesulfonate ]
Miron et al., PloS one 2011 : EMD significantly increased the expression of connexin 43 and N-cadherin at early time points ranging from 2 to 5 days