Tokiyasu et al., J Periodontol 2000
:
EMD down-regulated osteocalcin transcripts in cementoblasts and MC3T3-E1 cells and up-regulated osteopontin gene expression markedly in MC3T3-E1 cells and slightly in cementoblasts at day 8
Miron et al., Clin Oral Investig 2013
:
EMD promoted gene expression of various osteoblast differentiation markers including a number of collagen types and isoforms, SMAD intracellular proteins, osteopontin , cadherin, alkaline phosphatase, and bone sialoprotein