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CDKN1A — MAP2K2
Text-mined interactions from Literome
Ciccarelli et al., Molecular cancer 2005
(MAP Kinase Signaling System...) :
Furthermore, the TPA mediated post-transcriptional mechanism of p21WAF1 enhanced expression in RD cells is due to activation of the MEK/ERK pathway, as shown by transfections with constitutively active MEK1 or
MEK2 , which
induces p21WAF1 expression, and with ERK1 and ERK2 siRNA, which prevents p21WAF1 expression
Lotan et al., Cancer Res 2008
(Neoplasm Metastasis...) :
c-Jun NH2-terminal kinase activating kinase
1/mitogen activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis
involves growth arrest and
p21 up-regulation