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IRF6 — LDLR
Text-mined interactions from Literome
Harris et al., J Surg Res 2002
(Sepsis) :
Upregulation of the
LDL receptor increased the accumulation of ( 125 )
I-LPS in late endosomes ( P < 0.03 )
Ye et al., Inflamm Res 2009
(Inflammation) :
However,
LPS enhanced
LDL receptor expression, overcoming the suppression of LDL receptor induced by 25 microg/ml LDL and inappropriately increasing LDL uptake ( p < 0.05 )
Pang et al., J Hypertens 2012
:
In THP-1 cells, telmisartan significantly reduced
LPS induced tumor necrosis factor-a, inhibitor of ?B-a, monocyte chemotactic protein-1 (MCP-1) and lectin-like oxidized
low-density lipoprotein receptor-1 gene expression and MCP-1 directed migration
Pang et al., Biochim Biophys Acta 2012
(Inflammation) :
Minocycline inhibited
LPS induced
activation of the lectin-like oxidized
low density lipoprotein receptor-1 ( LOX-1 ), NF-?B, LPS induced TNF-a factor ( LITAF ) and the Nur77 nuclear receptor
Morishita et al., J Dent Res 2013
(Periodontitis) :
In addition,
LPS stimulated the expression of
LDL-receptor protein on RAW 264.7 cells and enhanced the internalization of LDL