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IRF6 — LYN
Text-mined interactions from Literome
Napolitani et al., Eur J Immunol 2003
:
We show that
LPS induces activation of c-Src and
Lyn in human DC
Yan et al., Infect Immun 2004
:
LPS activated the src-like kinases p59hck ( HCK ) and p58fgr ( FGR ) in both adult and newborn PMNs but
increased the activation of
p53/56lyn ( LYN ) only in adult cells
Su et al., Clin Chim Acta 2006
:
Src,
Lyn and MAPKs are
involved in LTA and
LPS signaling in murine macrophages
Cross et al., J Immunol 2008
:
CD45 affected the phosphorylation state of Lyn, Hck, and Fyn in bone marrow derived DCs and dysregulated
LPS induced
Lyn activation
Keck et al., J Immunol 2010
:
LPS stimulated
Lyn ( -/- ) BMM Phis produced significantly more IL-6, TNF-alpha, and IFN-alpha/beta compared with wild type ( WT ) BMM Phis, suggesting that Lyn is able to control both MyD88- and TRIF dependent signaling pathways downstream of TLR4
Stefanová et al., J Biol Chem 1993
:
LPS rapidly
activates CD14 associated
p56lyn simultaneously with PTKs p58hck and p59c-fgr
Geng et al., Proc Natl Acad Sci U S A 1994
:
We show that
LPS activates the protein tyrosine kinase ( PTK )
p56lyn and that this is associated with tyrosine phosphorylation of the protooncogene product Vav