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PCNA — POLL
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
PCNA
—
POLL
(direct interaction, pull down)
Haracska et al., Mol Cell Biol 2002*
-
IRef Biogrid Interaction:
PCNA
—
POLL
(direct interaction, pull down)
Maga et al., J Biol Chem 2002*
-
IRef Biogrid Interaction:
PCNA
—
POLL
(direct interaction, pull down)
Shimazaki et al., Genes Cells 2002*
-
IRef Hprd Interaction:
PCNA
—
POLL
(in vitro)
Haracska et al., Mol Cell Biol 2002*, Shimazaki et al., Genes Cells 2002*, Maga et al., J Biol Chem 2002*, Frouin et al., Nucleic Acids Res 2005*
-
IRef Hprd Interaction:
PCNA
—
POLL
(in vivo)
Haracska et al., Mol Cell Biol 2002*, Shimazaki et al., Genes Cells 2002*, Maga et al., J Biol Chem 2002*, Frouin et al., Nucleic Acids Res 2005*
-
IRef Ophid Interaction:
PCNA
—
POLL
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Maga et al., FASEB J 2004
:
Given the high rate of frameshift mutations induced by pol lambda and its ability to bypass abasic sites, accurate
regulation of
pol lambda activity by
PCNA and p21 concerted action might be important for preventing genetic instability
Shimazaki et al., Genes Cells 2005
:
Through direct binding,
PCNA suppressed the distributive nucleotidyltransferase activity of
Pol lambda
Lebedeva et al., Biochim Biophys Acta 2005
:
FEN1 and
PCNA stimulate the strand displacement activity of
Pol lambda