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IL18 — IL1A

Text-mined interactions from Literome

Dinarello et al., Methods 1999 (Infection...) : IL-18 induces gene expression and synthesis of tumor necrosis factor (TNF), IL-1 , Fas ligand, and several chemokines
De Caterina et al., Am J Clin Nutr 2000 (Arteriosclerosis) : Consumption of the n-3 fatty acid docosahexaenoic acid ( DHA ; 22 : 6n-3 ) reduced endothelial expression of vascular cell adhesion molecule 1 ( VCAM-1 ), E-selectin, intercellular adhesion molecule 1 ( ICAM-1 ), interleukin 6 (IL-6), and IL-8 in response to IL-1 , IL-4, tumor necrosis factor, or bacterial endotoxin, with a half-maximal inhibitory concentration ( IC ( 50 ) ) of 1-25 micromol, ie, in the range of nutritionally achievable plasma concentrations
Zeyse et al., Biol Reprod 2000 : Induction of interleukin-1alpha production in murine Sertoli cells by interleukin-1
Lu et al., J Immunol 2000 : IL-1alpha or other secreted factor ( s ) from chlamydia infected epithelial cells as well as chlamydial structural component ( s ) were not involved in inducing IL-18 secretion
Jablonska et al., Immunol Invest 2001 : In the present study we investigated the effect of IL- 18 on the production of IL-1beta, IL-1Ra and sIL-1RII by human neutrophils
Veenstra et al., J Immunol 2002 (Neoplasms) : In contrast, IL-1alpha, IL-1beta , TNF-alpha, IFN-gamma-inducible protein-10, and Th2 cytokines such as IL-4 and IL-10 did not induce IL-18BPa
Wheeler et al., J Neurochem 2003 : IL-18 induced intracellular expression of IL-1 alpha and proIL-1 beta, and release of IL-6 from mixed glia
Shirasawa et al., Proc Natl Acad Sci U S A 2004 (Dermatitis) : Of interest is that in WT keratinocytes, both IL-1alpha and the secreted form of EP induced down-regulation of IL-18 mRNA expression, which overexpression in the epidermis was reported to induce skin inflammation in mice, whereas the down-regulation of IL-18 induced by IL-1alpha was impaired in EP ( -/- ) keratinocytes
Stuyt et al., J Endotoxin Res 2005 (Acute-Phase Reaction...) : IL-18 is a pro-inflammatory cytokine of the IL-1 family and it induces IL-1 , TNF, and IL-6, all of which are endogenous pyrogens
Van Damme et al., J Invest Dermatol 1990 : This study focuses on interferon-beta (IFN-beta), interleukin-6 (IL-6), and interleukin-8 (IL-8) production by fibroblasts and epithelial cells in response to interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha)
Li et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2010 : Transcription of IL-1ß , IL-10 and IL-12 p40 mRNA was enhanced at 2 h after oxLDL stimulation ( P < 0.01 ), and transcription of IL-1ß, IL-10 and IL-18 increased significantly at 50 h compared to 2 h, whereas IL-12 decreased significantly at 50 h compared to 2 h ( P < 0.01 )
Elias et al., Chest 1990 (Pneumonia...) : To understand the processes regulating inflammation and fibrosis in the human lung, we characterized the effects of recombinant interleukin-1 , tumor necrosis factor, and gamma interferon on fibroblast proliferation, collagen production, interleukin-1-alpha production, interleukin-1-beta production, and interleukin-6 production
Lichtnekert et al., PloS one 2011 (Glomerulonephritis...) : In contrast to other cytokines the secretion of IL-1ß and IL-18 requires a second stimulus that activates the inflammasome-ASC-caspase-1 pathway to cleave pro-IL-1ß and -IL-18 into their mature and secretable forms
Mutamba et al., Eur J Immunol 2012 : Furthermore, IL-1F8 stimulated increased CD40 and CD80 expression and IL-18 and IL-12 p70 production by MDDCs, which induced proliferation of IFN-? producing CD3 ( + ) lymphocytes ( indicative of inflammatory Th1 subsets )
Wu et al., Blood 2013 (Dengue...) : We found that DV induced high levels of IL-1ß and IL-18 from GM-M? ( inflammatory macrophage ) and caused cell death ( pyroptosis ), whereas M-M? ( resting macrophage ) did not produce IL-1ß and IL-18 on DV infection even with lipopolysaccharide priming
Seckinger et al., J Immunol 1987 (Fever) : A urine inhibitor of interleukin 1 activity affects both interleukin 1 alpha and 1 beta but not tumor necrosis factor alpha
Grosset et al., Blood 1995 : In vitro biosynthesis of leukemia inhibitory factor/human interleukin for DA cells by human endothelial cells : differential regulation by interleukin-1 alpha and glucocorticoids
Boxman et al., J Invest Dermatol 1993 : Low interleukin-1 activity was most probably not due to inhibition of interleukin-1 alpha production in squamous carcinoma cells-4/3T3 co-cultures because interleukin-1 alpha messenger RNA expression in squamous carcinoma cells-4 cells remained unchanged in the presence of 3T3 cells
Puren et al., J Clin Invest 1998 : IL-18 did not induce antiinflammatory cytokines, IL-1Ra , or IL-10, although IL-18 induction of TNFalpha was inhibited by IL-10
Dinarello et al., J Allergy Clin Immunol 1999 : IL-18 induces gene expression and synthesis of TNF, IL-1 , Fas ligand, and several chemokines