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GJA1 — RHOA

Text-mined interactions from Literome

Matsuda et al., J Mol Cell Cardiol 2006 : Furthermore, the translocation of Cx43 to longitudinal cell termini was prevented by the inhibition of Rac1, but not RhoA
Suh et al., Stem Cells Dev 2012 : Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex ... In conclusion, laminin-111 stimulated mESC proliferation through a reduction of GJIC via RhoA mediated Cx43 phosphorylation and Cx43/ZO-1/drebrin complex instability mediated Cx43 degradation
Ponsaerts et al., PloS one 2012 : RhoA activation and inhibition of Cx43-hemichannel activity were both prevented by pre-treatment of the cells with C3-toxin as well as knock down of RhoA by siRNA