Gene interactions and pathways from curated databases and text-mining

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TNF — TREM2

Text-mined interactions from Literome

Chen et al., Exp Mol Pathol 2008 (Endotoxemia) : IL-1beta and TNFalpha upregulated TREM-1 and TREM-3 expression and suppressed TREM-2 expression in macrophages and endothelial cells
Ormsby et al., Blood 2011 (Agammaglobulinemia...) : Importantly, TREM-1 induced production of the pro-inflammatory cytokines, TNF-a and IL-8, and up-regulation of activation/differentiation cell surface markers were impaired in Btk knockdown cells