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TNF — TREM2
Text-mined interactions from Literome
Chen et al., Exp Mol Pathol 2008
(Endotoxemia) :
IL-1beta and
TNFalpha upregulated TREM-1 and TREM-3 expression and
suppressed TREM-2 expression in macrophages and endothelial cells
Ormsby et al., Blood 2011
(Agammaglobulinemia...) :
Importantly,
TREM-1 induced production of the pro-inflammatory cytokines,
TNF-a and IL-8, and up-regulation of activation/differentiation cell surface markers were impaired in Btk knockdown cells