Gene interactions and pathways from curated databases and text-mining

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PRKAB2 — ZGLP1

Text-mined interactions from Literome

Huisamen et al., Cardiovasc J S Afr 2008 (Disease Models, Animal...) : GLP-1 could not directly activate protein kinase B ( also called Akt ) or the extracellular regulated kinases Erk1/2 in hearts or cardiocytes under normoxic conditions, but phosphorylation of the AMP activated kinase (AMPK) on Thr ( 172 ) was enhanced
Hurtado-Carneiro et al., Mol Neurobiol 2012 : Therefore, we investigated the coordinated effects of glucose and GLP-1 on the expression and activity of AMPK and p70S6K in the areas involved in the control of feeding ... The effect of GLP-1 on the expression and activities of AMPK and p70S6K was studied in hypothalamic slice explants exposed to low- and high-glucose concentrations by quantitative real-time RT-PCR and by the quantification of active phosphorylated protein levels by immunoblot
Moberly et al., Basic Res Cardiol 2013 (Diabetes Mellitus, Type 2...) : No evidence for GLP-1 mediated activation of cAMP/PKA or AMPK signaling in lean or obese hearts was observed