Gene interactions and pathways from curated databases and text-mining

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CXCL3 — INS

Text-mined interactions from Literome

Wurm et al., Cytokine 2008 : Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway ... Inhibition of the phosphatidylinositol 3-kinase by wortmannin or the mammalian target of rapamycin by rapamycin did not influence insulin mediated CXCL8 induction ... In contrast, blockage of the ERK-specific MAP kinase MEK with PD98059, that prevents phosphorylation of ERK1/ERK2, abrogated insulin induced CXCL8 release in primary monocytes
Farquharson et al., Mol Biol Rep 2012 (Colonic Neoplasms...) : In contrast to leptin, insulin significantly reduced CCL20 and CXCL11 and increased CXCL3 expression