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IL5 — PARP15
Text-mined interactions from Literome
Dantzer et al., Mol Cell Biol 2004
:
In addition, our data show that
PARP activity
regulates the DNA binding activity of
TRF2 via both a covalent heteromodification of the dimerization domain of TRF2 and a noncovalent binding of poly ( ADP-ribose ) to the myb domain of TRF2
VirĂ¡g et al., Med Sci Monit 2004
(Asthma...) :
The production of TNF- alpha and IL-12, but not
IL-5 or IL-13, was also
suppressed by
PARP inhibition
Ye et al., Nat Genet 2004
:
TRF1 itself can be
inhibited by the poly ( ADP-ribose ) polymerase (
PARP ) activity of its interacting partner tankyrase 1, which abolishes its DNA binding activity in vitro and removes the TRF1 complex from telomeres in vivo