◀ Back to BDNF

BDNF — IL2RB

Text-mined interactions from Literome

Giehl et al., J Neurosci 2001 : The neurotrophins nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) promote neuronal survival via tyrosine kinase ( Trk ) receptors, whereas NGF and BDNF can also induce apoptosis in developing neurons through p75 ( NTR ) receptors in the absence of their respective Trk receptors
Chaldakov et al., Arch Physiol Biochem 2001 (Coronary Artery Disease...) : Here we report that ( i ) both the amount and the immunoreactivity of NGF was reduced and the expression of p75NGF receptor and the number of mast cell increased in human atherosclerotic coronary arteries ( n = 12 ) compared with control specimens ( n = 9 ) obtained from autopsy cases, and ( ii ) NGF and BDNF plasma levels were reduced in patients with metabolic syndrome ( n = 23 ) compared with control subjects ( n = 10 )
Formaggio et al., Mol Cell Neurosci 2011 : NGF increased p75 expression exclusively in cholinergic neurons, whereas BDNF induced p75 expression only in a subset of GABAergic neurons ( p75 ( + ) /GAD67 ( + ) /ChAT ( - ) ) through a p75- and tyrosine-kinase dependent mechanism