Gene interactions and pathways from curated databases and text-mining

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CREBBP — E2F1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Suzuki et al., Int J Cancer 2000 (Mouth Neoplasms...) : TSA enhanced the protein expression of p21 ( WAF1 ), CREB binding protein , cyclinE, cyclin A, Bak and Bax, while it reduced the expression of E2F-1 , E2F-4, HDAC1, p53 and hyperphosphorylated form of Rb
Mussi et al., Mol Endocrinol 2006 : Furthermore, overexpression of E2F1 significantly increases the promoter activity of the endogenous SRC-3 gene and boosts SRC-3 expression in vivo