Gene interactions and pathways from curated databases and text-mining

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IL5 — SEA

Text-mined interactions from Literome

Farah et al., Scand J Immunol 2000 (Granuloma...) : Group B animals had low SEA induced IFN-gamma levels and elevated IL-5 levels, although these were lower than group C. SEA induced IL-10 was low in both groups A and B as compared to group C ( P < 0.01 )
King et al., Parasite Immunol 2001 (Schistosomiasis mansoni) : By contrast, CD4+ splenocytes produced comparatively little cytokine release by endogenous antigen, whereas exogenous SEA strongly induced IL-4, IL-5 , IL-10 and IFN-gamma production and lymphocyte proliferation that correlated poorly with the dynamics of granulomatous inflammation
Shen et al., Parasite Immunol 2003 (Schistosomiasis japonica) : S. japonicum soluble worm antigen ( SWAP ) and soluble egg antigen (SEA) stimulated IL-4, IL-5 and IFN-gamma production in whole-blood cultures were measured by ELISA
Ghadimi et al., Immunobiology 2008 (Hypersensitivity) : Lactobacilli and bifidobacteria reduced SEA stimulated IL-4 and IL-5 production more effectively in PBMCs from healthy subjects than from allergic patients
Tweyongyere et al., BMC infectious diseases 2011 (Pregnancy Complications, Parasitic...) : There was some evidence that maternal infection intensity was positively associated with cord blood IL-5 and IL-13 responses to SWA, and IL-5 responses to SEA , and that this association was modified by treatment with praziquantel
Oliveira et al., Am J Trop Med Hyg 2012 (Disease Susceptibility...) : Mononuclear cells of resistant subjects produced higher levels of interleukin-5 (IL-5) , IL-13 and interferon-? upon stimulation with soluble egg antigen (SEA) compared with infected persons
Ferreira et al., Mem Inst Oswaldo Cruz 2012 (Chronic Disease...) : We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-a, interleukin (IL)-4 and IL-10 secretion in both OST and non infected individuals ( NI )
De Souza et al., Journal of parasitology research 2012 : The levels of IL-5 in response to SEA were higher in individuals with moderate to severe fibrosis ( 310.9?pg/mL ) compared to individuals without fibrosis ( 36.8?pg/mL ; P = 0.0418 )
König et al., Int Arch Allergy Immunol 1995 (Dermatitis, Atopic) : In contrast to normal donors T cells from donors with AD predominantly express mRNA for IL-4, IL-5 , and only diminished levels for IFN-gamma and IL-12 upon stimulation with SEB and SEA
Hobeika et al., Biochem Biophys Res Commun 1996 : A synthetic peptide of this region, SEA ( 121-149 ), blocks SEA binding to class II MHC molecules and induces interleukin-1 and tumor necrosis factor production in monocytes