◀ Back to SMARCA4

ESR1 — SMARCA4

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: ESR1 → SMARCA4 (directlyIncreases, SMARCA4 Activity, ESR1 Activity)
  Evidence: Transcriptional activation involves alterations in chromatin structure mediated by ATP-dependent chromatin-remodeling enzymes in conjunction with factors that contain histone acetyltransferase (HAT) activity [17]. Consistent with this concept is the observation that ER recruits BRG1, a mammalian homologue of a component of the SWI/SNF chromatin remodeling complex, to EREs in a cooperative manner with HATs [18]. Further, many ER coactivators possess intrinsic HAT activities, including CBP/p300, p...
• OpenBEL Selventa BEL large corpus: ESR1 → Complex of ESR1-SMARCA4 (directlyIncreases, ESR1/SMARCA4 Activity)
  Evidence: Transcriptional activation involves alterations in chromatin structure mediated by ATP-dependent chromatin-remodeling enzymes in conjunction with factors that contain histone acetyltransferase (HAT) activity [17]. Consistent with this concept is the observation that ER recruits BRG1, a mammalian homologue of a component of the SWI/SNF chromatin remodeling complex, to EREs in a cooperative manner with HATs [18]. Further, many ER coactivators possess intrinsic HAT activities, including CBP/p300, p...

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ESR1 — SMARCA4 (direct interaction, two hybrid) Ichinose et al., Gene 1997*
• IRef Biogrid Interaction: ESR1 — SMARCA4 (direct interaction, pull down) DiRenzo et al., Mol Cell Biol 2000*
• IRef Biogrid Interaction: ESR1 — SMARCA4 (physical association, affinity chromatography technology) Okada et al., EMBO Rep 2008
• IRef Hprd Interaction: ESR1 — SMARCA4 (in vivo) Ichinose et al., Gene 1997*
• IRef Hprd Interaction: ESR1 — SMARCA4 (two hybrid) Ichinose et al., Gene 1997*
• IRef Intact Interaction: Complex of ESR1-SMARCC2-SMARCB1-SMARCA4 (association, anti tag coimmunoprecipitation) Okada et al., EMBO Rep 2008
• IRef Intact Interaction: ESR1 — SMARCA4 (physical association, anti bait coimmunoprecipitation) Okada et al., EMBO Rep 2008
• IRef Intact Interaction: ESR1 — SMARCA4 (colocalization, fluorescence microscopy) Okada et al., EMBO Rep 2008
• IRef Ophid Interaction: ESR1 — SMARCA4 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005