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GNAQ — RHOA

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: RHOA → GNAQ (increases, GNAQ Activity, RHOA Activity) Zeng et al., J Biol Chem 2003*
  Evidence: Our most recent works show that pertussis toxin-sensitive G proteins and Gbetagamma subunits are required for Flt-1-mediated down-regulation of human umbilical vein endothelial cell (HUVEC) proliferation and that Gq/11 proteins are required for KDR-mediated RhoA activation and HUVEC migration.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS CORUM GNAQ-GEFT-RHOA complex: GNAQ-GEFT-RHOA complex complex (ARHGEF25-GNAQ-RHOA) Lutz et al., Science 2007*
• IRef Corum Interaction: Complex of RHOA-ARHGEF25-GNAQ (association, x-ray crystallography) Lutz et al., Science 2007*