Gene interactions and pathways from curated databases and text-mining

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CD28 — RPL17

Text-mined interactions from Literome

Latchman et al., Nat Immunol 2001 : At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals
Salama et al., J Exp Med 2003 (Encephalomyelitis, Autoimmune, Experimental) : In both wild-type ( WT ) and CD28-deficient mice, PD-1 blockade resulted in accelerated and more severe disease with increased CNS lymphocyte infiltration