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FAS — RAC1

Text-mined interactions from Literome

Li et al., Mol Cell Biol 2003 : Forced localization of CRKL to FAs ( FA-CRKL ) by itself was sufficient to induce activation of Rac1 and Cdc42 and rescued haptotaxis defects of mouse embryonic fibroblasts ( MEFs ) lacking Src, Yes, and Fyn, three broadly expressed Src family members required for integrin induced migration
Ramaswamy et al., J Immunol 2007 (Autoimmune Diseases) : The ability of Rac1 to sensitize T cells to Fas induced apoptosis correlated with Rac mediated cytoskeletal reorganization, dephosphorylation of the ERM ( ezrin/radixin/moesin ) family of cytoskeletal linker proteins, and the translocation of Fas to lipid raft microdomains
Birukova et al., Am J Physiol Lung Cell Mol Physiol 2008 : Our results demonstrate that OxPAPC induced Rac dependent , Rho independent peripheral accumulation of paxillin containing FAs and time dependent paxillin phosphorylation
Kang et al., Am J Pathol 2010 (Neoplasms, Experimental) : Rac1 , a binding partner of VASP, acts in tandem with VASP to regulate FAs
Brenner et al., J Biol Chem 1997 : Fas- or ceramide induced apoptosis is mediated by a Rac1 regulated activation of Jun N-terminal kinase/p38 kinases and GADD153