Gene interactions and pathways from curated databases and text-mining

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CBLB — TRAF6

Pathways - manually collected, often from reviews:

  • NCI Pathway Database CD40/CD40L signaling: PI3K Class I family/CBL-b complex (CBLB) → CD40/CD40L (trimer)/TRAF6 complex (CD40LG-CD40-TRAF6) (modification, collaborate)
    Arron et al., J Biol Chem 2001
    Evidence: physical interaction, other species
  • NCI Pathway Database CD40/CD40L signaling: PI3K Class I family/CBL-b complex (CBLB) → CD40/CD40L (trimer)/TRAF6/PI3K Class I family/CBL-b complex (CD40LG-CD40-TRAF6-CBLB) (modification, collaborate)
    Arron et al., J Biol Chem 2001
    Evidence: physical interaction, other species
  • NCI Pathway Database CD40/CD40L signaling: CD40/CD40L (trimer)/TRAF6 complex (CD40LG-CD40-TRAF6) → CD40/CD40L (trimer)/TRAF6/PI3K Class I family/CBL-b complex (CD40LG-CD40-TRAF6-CBLB) (modification, collaborate)
    Arron et al., J Biol Chem 2001
    Evidence: physical interaction, other species

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *