Gene interactions and pathways from curated databases and text-mining

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E2F1 — EGF

Text-mined interactions from Literome

Lee et al., Curr Eye Res 2001 : However, EGF and KGF, but not HGF, up-regulated expression of the E2F-1 pRB binding protein gene
Amrani et al., Am J Physiol Lung Cell Mol Physiol 2003 : Expression array analysis of 23 cell cycle related genes showed that IFN-gamma inhibited EGF induced increases in E2F-1 expression, whereas induction of c-myc, cyclin D2, Egr-1, and mdm2 were unaffected
Hanada et al., Mol Carcinog 2006 : Promoter mutagenesis studies showed that EGF induced activation of B-Myb promoter required both E2F and EGFR target sites
Loomis et al., Cancer Res 2007 : We observed that C/EBPalpha blocked Ras induced and epidermal growth factor induced E2F activity in keratinocytes and also blocked Ras induced cell transformation and cell cycle progression
Zheng et al., Cancer Res 2009 (Prostatic Neoplasms) : E2F1 up-regulated the production of EGR1 induced growth factors, epidermal growth factor , platelet derived growth factor, and insulin-like growth factor II, which in turn activated the phosphoinositide-3-kinase/Akt pathway to resist drug induced apoptosis
Kitano et al., Am J Physiol 1998 : We examined epidermal growth factor (EGF)- and epinephrine stimulated mitogen activated protein kinase kinase ( MEK) 1 and MEK2 activities, DNA polymerase alpha activity, and EGF stimulated E2F DNA binding activity in primary cultured hepatocytes from 6- and 24-mo-old rats ... EGF stimulated E2F ( a transcription factor that regulates expression of the DNA polymerase alpha gene ) binding to DNA was reduced with age