Fernandez-Patron et al., Thromb Haemost 1999
:
The inhibitors of protein tyrosine kinase , herbymicin A, genistein, and tyrphostin 1288 ( 1 to 100 microM ), enhanced the basal release of MMP-2 but did not affect the thrombin induced secretion of MMP-2
Hauck et al., EMBO J 2002
(Lung Neoplasms) :
Transient FRNK expression in human 293 cells inhibited exogenous MMP-2 promoter activity and overexpression of wild-type but not catalytically-inactive ( Ala-404 ) MMP-2 rescued v-Src stimulated Matrigel invasion in the presence of FRNK
Canel et al., Br J Cancer 2008
(Carcinoma, Squamous Cell...) :
FRNK expression resulted in a downregulation of MMP-2 and MMP-9 expression