Gene interactions and pathways from curated databases and text-mining

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KLRD1 — TNF

Text-mined interactions from Literome

Carretero et al., Eur J Immunol 2000 (Leukemia, Basophilic, Acute...) : By the use of the MEK inhibitor PD098059 we demonstrate that the MAPK pathway participates in the CD94 dependent TNF-alpha production and cytotoxicity
Zhou et al., J Immunol 2008 (Orthomyxoviridae Infections...) : TNF-alpha produced by Ag-specific CD8+ T cells appears primarily responsible for this immunopathology, and we have examined the negative regulation of CD8+ TNF production by CD94/NKG2A engagement with its receptor, Qa-1b
Aramburu et al., J Immunol 1993 : It is noteworthy that the Kp43 mediated production of TNF-alpha was partially inhibited by anti-CD18, anti-CD11a and anti-ICAM-1 mAb that blocked LFA-1 dependent cellular interactions, which impaired NK cell aggregation and, moreover, was dependent on the presence of extracellular Mg2+, thus suggesting that the leukocyte integrin is involved in the activation process triggered through Kp43
Poggi et al., Int Immunol 1997 : In addition, cross linking of p40 molecules strongly inhibited the CD94 induced tumor necrosis factor-alpha and IFN-gamma production