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KLRD1 — TNF
Text-mined interactions from Literome
Carretero et al., Eur J Immunol 2000
(Leukemia, Basophilic, Acute...) :
By the use of the MEK inhibitor PD098059 we demonstrate that the MAPK pathway participates in the
CD94 dependent
TNF-alpha production and cytotoxicity
Zhou et al., J Immunol 2008
(Orthomyxoviridae Infections...) :
TNF-alpha produced by Ag-specific CD8+ T cells appears primarily responsible for this immunopathology, and we have examined the negative
regulation of CD8+
TNF production by
CD94/NKG2A engagement with its receptor, Qa-1b
Aramburu et al., J Immunol 1993
:
It is noteworthy that the
Kp43 mediated production of
TNF-alpha was partially inhibited by anti-CD18, anti-CD11a and anti-ICAM-1 mAb that blocked LFA-1 dependent cellular interactions, which impaired NK cell aggregation and, moreover, was dependent on the presence of extracellular Mg2+, thus suggesting that the leukocyte integrin is involved in the activation process triggered through Kp43
Poggi et al., Int Immunol 1997
:
In addition, cross linking of p40 molecules strongly inhibited the
CD94 induced
tumor necrosis factor-alpha and IFN-gamma production