Gene interactions and pathways from curated databases and text-mining

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CISH — SOCS2

Text-mined interactions from Literome

Karlsson et al., Mol Cell Endocrinol 1999 : Here we demonstrate that Socs-2 and Cis mRNA expression in rat liver is dependent on the presence of growth hormone (GH), and that GH induce Cis mRNA expression in cultures of primary rat hepatocytes
Dogusan et al., J Neuroimmunol 2000 (Leukemia) : In tonsillar cells, CIS expression was increased and SOCS-2 was induced by IL-1beta, IL-6, PRL and GH
Johnson et al., J Endocrinol 2001 (Sepsis) : GH induced SOCS-2 and CIS in the CLP rat despite resistance with respect to IGF-I generation, and parenteral feeding induced CIS in the CLP rat
Cwikel et al., Exp Hematol 2001 : However, CIS-1 was induced by PRL < IL-3 < PRL+IL-3, whereas CIS-2 expression was induced by PRL = IL-3 < PRL+IL-3
Lavens et al., J Cell Sci 2006 : Furthermore, although SOCS2 does not associate with Y985 of the leptin receptor, we find that SOCS2 can block interaction of CIS with this position
Piessevaux et al., J Biol Chem 2006 : This SOCS2 effect was SOCS box dependent , required recruitment of the elongin BC complex, and coincided with degradation of target SOCS proteins