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GRAP2 — IL12A
Text-mined interactions from Literome
Feng et al., J Immunol 1999
:
Extracellular signal related kinase ( ERK ) and
p38 mitogen activated protein ( MAP ) kinases differentially
regulate the lipopolysaccharide mediated induction of inducible nitric oxide synthase and
IL-12 in macrophages : Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase
NĂ©meth et al., Biochim Biophys Acta 2001
:
Furthermore, the inhibitory effect of amiloride on
IL-12 p40 production was not a
result of interference with the activation of the
p38 and p42/44 mitogen activated protein kinases or c-Jun kinase
Kang et al., Biochem Pharmacol 2002
:
Berberine induced
IL-12 p40 production and
activation of
p38 mitogen activated protein kinase ( MAPK ) in dose dependent manners, which were significantly inhibited by p38 MAPK inhibitors and yohimbine, indicating that p38 MAPK and alpha ( 2 ) -adrenergic receptor were involved in the induction of IL-12 p40 production in mouse macrophages by berberine
Dai et al., J Immunol 2005
:
Gal-9 induced phosphorylation of the MAPK p38 and ERK1/2 in DCs, and an inhibitor of
p38 signaling, but not inhibitors of signaling by either ERK1/2 or PI3K,
blocked Gal-9 induced up-regulation of costimulatory molecule expression and
IL-12 production
Koch et al., Respir Med 2007
(Asthma) :
The modulatory
role of extracellular signal regulated kinase ( ERK ) -1/-2,
p38mitogen activated protein kinase ( MAPK ) and dexamethasone on
IL-12 induced T-bet and IFNgamma expression was assessed in peripheral blood lymphocytes of 10 atopic asthmatics and 10 nonatopic normals
Sodhi et al., Glycoconj J 2007
:
Pharmacological inhibitor of tyrosine kinase, PI3 kinase, protein kinase C, p42/44,
p38 , JNK and intracellular calcium immobilizing agent down
regulated the WGA induced expression of cytokines TNF-alpha, IL-1beta,
IL-12 and IFN-gamma
Kang et al., Cytokine 2009
:
Induction of
IL-12 by LMM in peritoneal macrophages
involved NF-kappaB,
p38 and JNK, but not ERK1/2