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IL10 — POLDIP2
Text-mined interactions from Literome
Schwacha et al., Shock 2003
(Burns) :
Inhibition of
p38 MAP kinase activity
attenuated IL-10 production and abrogated the enhanced IL-10 response induced by alphaCD11b, whereas ERK 1/2 inhibition had no effect
Kotani et al., Eur Respir J 2004
(Disease Models, Animal...) :
Physiological parameters, tumour necrosis factor (TNF)-alpha,
interleukin (IL)-8 and
activation of mitogen activated protein kinases ( extracellular signal regulated kinase ( ERK ) 1/2,
p38 and stress activated protein kinase ( SAPK ) / c-Jun N-terminal kinase (JNK) ) were measured
Chi et al., Proc Natl Acad Sci U S A 2006
(Shock, Septic) :
In response to TLR signals, MKP-1-deficient macrophages produced 5- to 10-fold higher
IL-10 , which could be
blocked by a
p38 MAPK inhibitor
Kalliolias et al., J Immunol 2008
:
IL-27 activates human monocytes via STAT1 and
suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and
p38