◀ Back to MMP9
MMP9 — RNF19A
Text-mined interactions from Literome
Simon et al., Exp Cell Res 2001
(Neoplasm Invasiveness...) :
While dominant negative
p38 and MKK-6 mutants
reduced MMP-9 promoter activity in CAT assays, a construct encoding an activating mutation in the MKK-6 protein potently stimulated it
Chakrabarti et al., J Leukoc Biol 2005
(MAP Kinase Signaling System) :
Inhibition of extracellular signal regulated kinase ( ERK ) 1/2 blocked IL-8 mediated MMP-9 release ; however, inhibition of
p38 mitogen activated protein kinase
had no effect on
MMP-9 release
Furundzija et al., Biochem Biophys Res Commun 2010
(Atherosclerosis) :
This involves activation of integrins and focal adhesion formation via inside-out
PI3-kinase/PKC/p38 dependent signaling, but does not
require MMP activation
Han et al., Oncol Res 2010
(Adenocarcinoma...) :
In contrast,
p38 inhibitor
reduced cell growth inhibition, apoptosis, and
MMP ( deltapsi ( m ) ) loss by MG132
Ranzato et al., Exp Dermatol 2011
:
Zymography and Western blot analyses showed that exposure to 20 % ( v/v ) PL for 24 h induced an apparently ERK1/2- and
p38 dependent , NF-kappaB independent, translational upregulation of
MMP-9 in HaCaT, while HaCaT MMP-2 and fibroblast collagenases were almost unaffected
Miraglia et al., Journal of neuroinflammation 2013
(Brucellosis...) :
Inhibition of
p38 or Erk1/2 significantly
diminished MMP-9 secretion, and totally abrogated production of this MMP when both MAPK pathways were inhibited simultaneously