Gene interactions and pathways from curated databases and text-mining

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PKN2 — TGFB1

Text-mined interactions from Literome

Deaton et al., J Biol Chem 2005 : Moreover, TGF-beta1 activated RhoA and its downstream target PKN ... Taken together, these results identify components of an important intracellular signaling pathway through which TGF-beta1 activates PKN to promote differentiation of SMCs
Su et al., Cell cycle (Georgetown, Tex.) 2007 : PKN activation via transforming growth factor-beta 1 ( TGF-beta 1 ) receptor signaling delays G2/M phase transition in vascular smooth muscle cells ... Our data demonstrate that Cdc25C activity is negatively regulated by TGF-beta1 stimulated PKN