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CCL2 — SLC22A3

Text-mined interactions from Literome

Tan et al., Zhonghua Yi Xue Za Zhi 2005 : To examine the effect of Bone Morphogenetic protein-7 (BMP-7) on Monocyte chemoattractant protein-1 ( MCP-1 ) induced epithelial-myofibroblast transition ( EMT ) in cultured renal proximal tubular cells ( HK-2 ) and the relationship between TGF-beta1-smad 3 expressions and MCP-1 induced EMT ... The results documented that MCP-1 may induce EMT of HK-2 cells in vitro, and this effect is related to up-regulated expression of TGF-beta1 and Smad 3 ... BMP-7 may partially inhibit MCP-1 induced EMT and this effect is related to the downregulated expression of TGF-beta1 and Smad 3 of the cells ... The results also suggest that MCP-1 induced EMT may involve the TGF-beta1 independent pathway of the cells
Lee et al., Lab Invest 2012 (Peritoneal Fibrosis) : In addition, MCP-1 induced EMT was significantly attenuated by anti-TGF-ß1 antibody