Belling et al., Int J Artif Organs 2013
:
Stimulation with IL-1ß induced an increase of the mesothelial PAR-1 expression whereas stimulation with glycosilated human serum albumin or the ligand thrombin itself resulted in decreased PAR-1 expression
Nieuwenhuizen et al., Scand J Immunol 2013
:
In contrast, stimulation of PBMCs with coagulation proteases resulted in thrombin mediated induction of IL-1ß and IL-6 cytokine production and PBMC cell proliferation in a PAR-1 dependent manner