Abraham et al., Mol Biol Cell 1992
:
We report here that TGF beta 1 induces not only a change in p34cdc2 kinase activity but a strong repression of p34cdc2 synthesis ... The E1A.928 mutant virus is able to maintain p34cdc2 expression and kinase activity, as well as pRB phosphorylation in the presence of TGF beta 1 , which may account for its ability to maintain cell cycle activity without directly sequestering pRB
Longstreet et al., Oncogene 1992
(Cell Transformation, Neoplastic) :
The results show that in the control CCL64 cells and in the myc transfected clones TGF-beta 1 regulation of p34cdc2 activity is maintained