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IRF5 — NOS2
Text-mined interactions from Literome
Pavlovic et al., Eur Cytokine Netw 1999
:
In conclusion,
IRF-1 contributes to cytokine induced islet
iNOS expression and cell death
De Stefano et al., J Mol Med (Berl) 2006
(Celiac Disease) :
The
role of NF-kappaB,
IRF-1 , and STAT-1alpha transcription factors in the
iNOS gene induction by gliadin and IFN-gamma in RAW 264.7 macrophages
Paun et al., PLoS Pathog 2011
(Disease Models, Animal...) :
Collectively, these results identify IRF-5 as a critical molecular switch for the development of Th1 immune responses following L. donovani infections and reveal an indirect
role of
IRF-5 in the regulation of
iNOS expression
Kamijo et al., Science 1994
(Tuberculosis) :
Thus,
IRF-1 is
essential for
iNOS activation in murine macrophages