Gene interactions and pathways from curated databases and text-mining

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GRB2 — JUN

Text-mined interactions from Literome

Hashimoto et al., J Biol Chem 1999 : Conversely, the EGF mediated c-Jun N-terminal kinase (JNK) activation is dependent on Shc, but not Grb2
Mendoza-Gamboa et al., Oncol Rep 2004 (Breast Neoplasms) : Inhibition of HER2/Grb2/Akt decreased AP-1 binding activity in HER2 transfected cells, but increased AP-1 activity in cells that are naturally HER2 overexpressing
Pomérance et al., J Biol Chem 1998 : Grb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor