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CLEC2D — IFNG

Text-mined interactions from Literome

Mathew et al., Mol Immunol 2004 : The LLT1 receptor induces IFN-gamma production by human natural killer cells ... We further demonstrate that in resting NK cells as well as in IL-2 activated NK cells LLT1 induced IFN-gamma production, but not cytotoxicity
Aldemir et al., J Immunol 2005 : Conversely, LLT1/CD161 interaction in the presence of a TCR signal enhanced IFN-gamma production by T cells
Bambard et al., Scand J Immunol 2010 : LLT1 mediated activation of IFN-gamma production in human natural killer cells involves ERK signalling pathway ... Previous studies showed that cross linking surface LLT1 with a monoclonal antibody stimulated NK cell IFN-gamma secretion but had no effect on cytotoxicity ... Phosphorylation studies of the signalling adaptor molecules confirmed that the ERK signalling pathway is associated with LLT1 mediated IFN-gamma production