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LOX — SRC

Text-mined interactions from Literome

Postovit et al., J Cell Biochem 2008 (Breast Neoplasms...) : Moreover, poorly invasive breast cancer cells displayed a marked increase in LOX dependent FAK/Src activation and cell migration following hypoxia/reoxygenation, but not in response to hypoxia alone
Laczko et al., Neuropathol Appl Neurobiol 2007 (Astrocytoma...) : While the catalytic function of LOX is essential for cross linking of ECM proteins, we also reported that LOX induced invasive and metastatic properties in breast tumour epithelial cells through hydrogen peroxide mediated FAK/Src activation
Baker et al., J Natl Cancer Inst 2011 (Colorectal Neoplasms...) : LOX showed an important role in CRC cell proliferation and metastasis and was dependent on the activation of SRC