Gene interactions and pathways from curated databases and text-mining

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IL2 — PDCD1LG2

Text-mined interactions from Literome

Chen et al., Int Immunopharmacol 2005 : Moreover, the significant damping effect of sinomenine on B7-H1 and B7-DC signals could promote IL-2 and IFN-gamma production by co-cultured CD4 ( + ) T cell
Saunders et al., Eur J Immunol 2005 : In this study, we demonstrate that on human T cells, PD-L2 acts only as a negative regulator of T cell activity, inhibiting proliferation, IL-2 production, and IFN-gamma production via its interaction with programmed death-1 (PD-1)
Nagamatsu et al., Hum Reprod 2009 : B7-H1 blockade on DSCs strongly enhanced T cell cytokine production ( IFN-gamma, TNF-alpha and IL-2 ), whereas B7-DC blockade had similar but more modest effects