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IRF6 — SYK

Text-mined interactions from Literome

Arndt et al., J Biol Chem 2004 : In addition, LPS stimulation of non suspended neutrophils activates Syk and phosphatidylinositol 3-kinase (PI3K) ... Furthermore we show that PI3K inhibition decreased LPS induced Syk activation suggesting that PI3K resides upstream of Syk in this pathway
Ulanova et al., J Endotoxin Res 2007 : We hypothesized that Syk is involved in inflammatory responses induced by the lipopolysaccharide (LPS)
Lu et al., PLoS Pathog 2012 (Inflammation...) : We found that LPS treated neutrophils induced phosphorylation of Syk resulting in the formation of a complex including TLR4, p-Syk, and p-CEACAM1, which in turn, recruited the inhibitory phosphatase SHP-1
Zhu et al., Int Immunopharmacol 2013 (Disease Models, Animal...) : These findings demonstrated that ß-glucan activation of Dectin1/Syk attenuated LPS induction of TLR4/MyD88/NF-?B and inhibited the LPS induced inflammation factors in mammary epithelial cells, thereby providing a possibly protective effect of ß-glucan in the prevention of LPS induced dysfunction in mammary epithelial cells