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IL8 — NM
Text-mined interactions from Literome
Godaly et al., Mol Microbiol 1998
:
P- and type 1-fimbriated E. coli triggered higher
interleukin (IL) 8 secretion and expression of functional IL-8 receptors than non fimbriated controls, and the increase in
neutrophil migration across infected cell layers was
inhibited by anti-IL-8 antibodies
Arbabi et al., J Immunol 1999
:
Inhibition of
IL-8 and TNF-alpha production by acute EtOH intoxication may
inhibit inflammatory focused
neutrophil migration and activation and may be a mechanism explaining the increased risk of trauma- and burn related infections
Godaly et al., J Leukoc Biol 2001
(Bacteriuria...) :
Interleukin (IL)-8 and CXCR1
direct neutrophil migration across the epithelial barrier into the lumen
Cullen et al., Gen Pharmacol 2000
:
In the presence of this antibody ( 10 microg/ml ),
neutrophil migration in
response to fMLP ( 10 nM ),
IL-8 ( 10 nM ) or LTB ( 4 ) ( 100 nM ) was not significantly different to that in the absence of antibody
Venuprasad et al., J Immunol 2002
:
We previously showed that CD28 is expressed on human peripheral blood neutrophils and plays an important role in CXCR-1 expression and
IL-8 induced
neutrophil migration
Ramos et al., Cytokine 2003
:
The aim of this study was to characterize the mediators released by mast cells responsible for
IL-8 induced
neutrophil migration ... It was observed that
IL-8 induces a dose dependent
neutrophil migration into peritoneal cavity of rats, but not into air-pouch cavity in which resident mast cells are not present ... The
neutrophil migration induced by
IL-8 into the peritoneal cavity was not observed when the peritoneal-resident mast cells were depleted by compound 48/80 or distilled water treatment ... The
IL-8 induced
neutrophil migration was observed not to be dependent on LTB ( 4 ), prostaglandins or TNF-alpha, since MK886, indomethacin or thalidomide were unable to block the IL-8 induced neutrophil accumulation ` in vivo ' or the release of neutrophil chemotactic factor `` in vitro '' by IL-8 stimulated mast cells ... However, dexamethasone, an inhibitor of the synthesis of pro-inflammatory cytokines, blocked the
neutrophil migration induced by
IL-8 `` in vivo '' and also inhibited the release of the neutrophil chemotactic factor by IL-8 stimulated mast cells ... In conclusion, we demonstrated that the
neutrophil migration induced by
IL-8 is dependent on CINC-1 release from mast cells
Di Cioccio et al., Immunology 2004
:
The signalling pathways leading to
CXCL8/IL-8 induced human
neutrophil migration have not been fully characterized
Bhatia et al., Injury 2005
(Respiratory Distress Syndrome, Adult...) :
IL-8 mediated
neutrophil migration was significantly increased on admission following major trauma and remained elevated for 3 days ( p < 0.05 )
Rambeaud et al., Vet Immunol Immunopathol 2006
(Mastitis, Bovine) :
This gene encodes a receptor for
interleukin-8 (IL-8) , a key
regulator of
neutrophil migration , killing and survival
Shin et al., Acta Otolaryngol 2006
(Nasal Polyps) :
Eosinophil migration was induced by RANTES and eotaxin, and
neutrophil migration was
induced by
IL-8 in HPECM
Alencar et al., Naunyn Schmiedebergs Arch Pharmacol 2007
:
Antiserum to TNF-alpha, but not IL-1 nor
IL-8 ,
inhibited the
neutrophil migration induced either by lectin or MNCF-VML
Huber et al., Science 1991
:
Regulation of transendothelial
neutrophil migration by endogenous
interleukin-8
Brkovic et al., J Leukoc Biol 2007
:
Pretreatment of neutrophils with Ang1 or Ang2 ( 10 nM ; 15 min ) potentiated
neutrophil migration induced by
CXCL8/IL-8 ( 1 or 10 nM ; 60 min ) by 263 % and 238 % and by 177 % and 164 %, respectively
, Science 1991
:
Figure 2, part B ( p. 100 ) in the report ``
Regulation of transendothelial
neutrophil migration by endogenous
interleukin-8 '' by A. R. Huber et al. ( 4 Oct., p. 99 ) was printed incorrectly
Van de Walle et al., J Immunol 2007
(Herpesviridae Infections...) :
Identification of gG as the responsible vCKBP was achieved by repeating similar experiments with supernatants from cells infected with a gG-negative mutant, which were unable to alter
IL-8 induced equine
neutrophil migration
Mariano-Oliveira et al., Int J Biochem Cell Biol 2008
:
The pre-treatment of cells with fragment 2 inhibited thrombin induced chemotaxis, while both fragments impaired
neutrophil migration induced by
interleukin-8
Galley et al., Br J Anaesth 2008
:
For chemotaxis,
neutrophil migration through a 5 microm membrane was measured in
response to formyl-methyl-leucine-phenylalanine ( FMLP ) or
IL-8 in the presence and absence of APC
Cecilio et al., Mediators Inflamm 1997
:
MNCF has been shown to be active in rats treated with dexamethasone, a glucocorticoid that usually inhibits the
neutrophil migration induced in this species by interleukin (IL)-1, tumour necrosis factor alpha (TNFalpha),
IL-8 , C5a and leukotriene B ( 4 ) ( LTB ( 4 ) )
Ribeiro et al., Immunology 1991
:
IL-8 causes in vivo
neutrophil migration by a cell dependent mechanism
Ben Yebdri et al., Eur J Immunol 2009
:
Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is
required for TLR1/2 induced
neutrophil migration by regulating
IL-8 secretion ... Altogether, these results show that extracellular nucleotides, via P2Y(2) and P2Y(6) receptors,
regulate neutrophil migration by controlling TLR2 induced
IL-8 release from human monocytes
Faccioli et al., Agents Actions 1990
:
Recombinant
interleukin-1 and tumor necrosis factor
induce neutrophil migration `` in vivo '' by indirect mechanisms
Pranchevicius et al., BMC biotechnology 2012
:
ArtinM is a d-mannose-specific lectin from Artocarpus integrifolia seeds that induces
neutrophil migration and activation, degranulation of mast cells, acceleration of wound healing,
induction of
interleukin-12 production by macrophages and dendritic cells, and protective T helper 1 immune response against Leishmania major, Leishmania amazonensis and Paracoccidioides brasiliensis infections
Planagumà et al., Clin Exp Immunol 2013
:
In conclusion, 15-epi-LXA4 is not a functional agonist or an antagonist of FPR2/ALX or CysLT1, shows no effect on IL-8 induced neutrophil survival and produces only moderate inhibition in
IL-8 mediated
neutrophil migration
Meliconi et al., Clin Exp Rheumatol 1995
(Arthritis, Rheumatoid...) :
Because of the
role of systemic
IL-8 in
neutrophil migration , serum IL-8 levels were also evaluated
Takahashi et al., Cardiovasc Res 1995
:
Effects of endogenous endothelial
interleukin-8 on
neutrophil migration across an endothelial monolayer ... The aim of this study was to investigate the
effects of
IL-8 on transendothelial
neutrophil migration using an in vitro three dimensional double chamber migration assay system
Loike et al., J Exp Med 1995
:
Fibrin regulates
neutrophil migration in
response to
interleukin 8 , leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine
Kuhns et al., J Immunol 1995
:
Subsequent release of
IL-8 during exudation may
regulate neutrophil migration into sites of inflammation
Smart et al., Am J Physiol 1994
:
TNF-alpha induced transendothelial
neutrophil migration is
IL-8 dependent
Perretti et al., Agents Actions 1993
:
Pharmacology of
interleukin-1 induced
neutrophil migration
Rot et al., Eur J Immunol 1993
:
In addition, we suggest that haptotaxis is responsible for
neutrophil migration induced by
NAP-1/IL-8 in standard Boyden-type chemotaxis assays and, in light of the ability of NAP-1/IL-8 to bind to the endothelial cell surface and the extracellular matrix, could also be of great significance in vivo
Agace et al., Eur Respir J 1996
:
Deliberate colonization of the human urinary tract with E. coli induced the local production of IL-8 and levels correlated with urinary neutrophil numbers suggesting a
role for
IL-8 in
neutrophil migration
Ponglertnapagorn et al., Microbiol Immunol 1996
(Bacterial Infections...) :
These data suggest that the level of IL-8 production in the airways of patients with lower respiratory tract infections is dependent on bacterial densities, and indicate the important
role of
IL-8 not only in
neutrophil migration but also in opsonophagocytic killing of bacteria in the lower respiratory tract
Liu et al., Ann N Y Acad Sci 1996
:
After a 4-h IL-1 beta activation,
neutrophil migration across EC was
dependent on
IL-8 and PAF
Godaly et al., Infect Immun 1997
:
Role of epithelial
interleukin-8 (IL-8) and neutrophil IL-8 receptor A in Escherichia coli
induced transuroepithelial
neutrophil migration
Ina et al., Am J Gastroenterol 1997
(Inflammatory Bowel Diseases) :
Mucosal
interleukin-8 is
involved in
neutrophil migration and binding to extracellular matrix in inflammatory bowel disease
Fujita et al., J Physiol Pharmacol 1997
:
Prior exposure of neutrophils to the gastric mucosal extract caused a dose dependent reduction in the
neutrophil migration induced by formyl-methionyl-leucyl-phenylalanine ( FMLP ), leukotriene B4 (LTB4) and
interleukin 8 (IL-8) without affecting the cell viability
White et al., J Biol Chem 1998
:
Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits
interleukin-8 induced
neutrophil migration
Tavares-Murta et al., Br J Pharmacol 1998
:
2. Pretreatment of mice with the NO synthase antagonist, NG-monomethyl-L-arginine ( L-NMMA, 15-60 mg kg ( -1 ) ), but not the inactive enantiomer D-NMMA ( 30 mg kg ( -1 ) ), prevented in a dose dependent manner the TNF-alpha,
IL-8 and MNCF mediated
inhibition of
neutrophil migration into thioglycollate challenged peritoneal cavities
Dias-Baruffi et al., Glycoconj J 1998
:
Heparin potentiates in vivo
neutrophil migration induced by
IL-8 ... Then, we evaluated the interference of heparan sulfate or heparin on in vivo
neutrophil migration induced by
IL-8 ... We studied the
neutrophil migration induced by
IL-8 ( 3.5 microg/animal ) into the rat peritoneal cavity depleted of mast cells ... These data suggest that heparin released from cytoplasmic granules may be the contribution of mast cells to
IL-8 induced
neutrophil migration