Gene interactions and pathways from curated databases and text-mining

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CXCL12 — ESR1

Text-mined interactions from Literome

Hall et al., Mol Endocrinol 2003 (Breast Neoplasms...) : This response is blocked by the pure ER antagonist ICI 182,780 and is not apparent in ER-negative ovarian cells, indicating that SDF-1 regulation is ERalpha mediated
Sauvé et al., Cancer Res 2009 : Both ERalpha and ERbeta were activated by SDF-1 in the presence of CXCR4 and by overexpression of a constitutively active CXCR4, indicating that CXCR4 signals to both receptors
Huang et al., Surgery 2011 (Myocardial Reperfusion Injury) : Estrogen induced SDF-1 production is mediated by estrogen receptor-a in female hearts after acute ischemia and reperfusion