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CD28 — FAS
Text-mined interactions from Literome
Crist et al., J Biol Chem 2003
:
These results served as the basis for structure/function analysis of the CD95L promoter to elucidate the mechanism for
CD28 mediated enhancement of
CD95L
Elias et al., J Immunol 2005
(Malaria...) :
Production of IFN-gamma ; up-regulation of CD69, CD40L,
CD95 ( Fas ), and CD95L ( Fas ligand ) ; and induction of apoptosis were also
affected by the lack of
CD28
Strauss et al., J Exp Med 2009
:
Naive human T cells triggered by antigen presenting cells expressing a membrane bound form of CD95 ligand (CD95L) or stimulated by anti-CD3 and
-CD28 antibodies in the
presence of recombinant
CD95L had reduced activation and proliferation, whereas preactivated, CD95-sensitive T cells underwent apoptosis
Walker et al., Immunology 1998
:
In Jurkat T cells, we show that
Fas signalling
leads to rapid and selective
CD28 down-regulation, and that this is associated with a specific decrease in mRNA for CD28, indicating that mechanisms exist which target CD28 at a transcriptional level