Gene interactions and pathways from curated databases and text-mining

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CSF2 — PTK7

Text-mined interactions from Literome

Kanakura et al., Blood 1990 (Leukemia, Megakaryoblastic, Acute) : We have investigated the effects of GM-CSF and IL-3 on protein tyrosine-kinase activity in a human cell line, MO7E, which proliferates in response to either factor ... These results suggest that tyrosine phosphorylation may be important for GM-CSF and IL-3 receptor mediated signal transduction and that cell proliferation may be, at least partially, regulated by a balance between CSF induced protein-tyrosine kinase activity and protein-tyrosine phosphatase activity
Beales et al., Eur J Gastroenterol Hepatol 1997 (Adenocarcinoma...) : The protein kinase C inhibitor staurosporine abolished the stimulatory effect of PMA on AGS cells, whereas the protein-tyrosine kinase inhibitor herbimycin A prevented the stimulation of GM-CSF production seen with H. pylori and both cytokines
Li et al., Leuk Res 1997 : Induction of macrophage colony stimulating factor receptor up-regulation in THP-1 human leukemia cells is dependent on the activation of c-fyn protein tyrosine kinase
Tsubokawa et al., Eur J Biochem 1997 (Leukemia, Myeloid, Acute) : In the current study, we demonstrated that a non-receptor-type protein-tyrosine kinase , Syk, was immediately activated by the stimulation with IL-3 or granulocyte colony stimulating factor in AML193 cells